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Journal article

Failure of the lipid peroxidation inhibitor, U74006F, to prevent postischemic selective neuronal injury.

Abstract:

The lipid peroxidation inhibitor, U74006F, was tested for neuroprotective properties using the rat four-vessel occlusion model. Adult Wistar rats (136) were randomized to receive pretreatment with either vehicle or U74006F, and exposed to either 15 min (n = 103) or 5 min (n = 33) of transient but severe forebrain ischemia. Surviving criterial animals were reperfused for 72 h, and in the multidose experiments, animals were injected with repeated doses of U74006F or vehicle during the reperfusi...

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Publication status:
Published

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Publisher copy:
10.1038/jcbfm.1992.35

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Stroke and Geratology
Role:
Author
Journal:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism More from this journal
Volume:
12
Issue:
2
Pages:
250-256
Publication date:
1992-03-01
DOI:
EISSN:
1559-7016
ISSN:
0271-678X
Language:
English
Keywords:
Pubs id:
pubs:80170
UUID:
uuid:c77fca60-e298-4141-9d02-d6281444ca3f
Local pid:
pubs:80170
Source identifiers:
80170
Deposit date:
2012-12-19

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