Journal article icon

Journal article

What evidence is there for the homology of protein-protein interactions?

Abstract:

The notion that sequence homology implies functional similarity underlies much of computational biology. In the case of protein-protein interactions, an interaction can be inferred between two proteins on the basis that sequence-similar proteins have been observed to interact. The use of transferred interactions is common, but the legitimacy of such inferred interactions is not clear. Here we investigate transferred interactions and whether data incompleteness explains the lack of evidence fo...

Expand abstract

Actions


Access Document


Files:

Authors


Publication date:
2012-01-01
URN:
uuid:c77d9fe8-ffeb-438c-b032-9d18e38fcd05
Local pid:
oai:eprints.maths.ox.ac.uk:1804

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP