Journal article
What evidence is there for the homology of protein-protein interactions?
- Abstract:
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The notion that sequence homology implies functional similarity underlies much of computational biology. In the case of protein-protein interactions, an interaction can be inferred between two proteins on the basis that sequence-similar proteins have been observed to interact. The use of transferred interactions is common, but the legitimacy of such inferred interactions is not clear. Here we investigate transferred interactions and whether data incompleteness explains the lack of evidence fo...
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Bibliographic Details
- Publication date:
- 2012-01-01
Item Description
- UUID:
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uuid:c77d9fe8-ffeb-438c-b032-9d18e38fcd05
- Local pid:
- oai:eprints.maths.ox.ac.uk:1804
- Deposit date:
- 2014-02-23
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- Copyright date:
- 2012
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