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Journal article : Review

Optimizing G6PD testing for Plasmodium vivax case management: why sex, counseling, and community engagement matter.

Abstract:

Safe access to the most effective treatment options for Plasmodium vivax malaria are limited by the absence of accurate point-of-care testing to detect glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common human genetic disorder. G6PD-deficient patients are at risk of life-threatening hemolysis when exposed to 8-aminoquinolines, the only class of drugs efficacious against P. vivax hypnozoites. Until recently, only qualitative tests were available in most settings. These accurat...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.12688/wellcomeopenres.15700.1

Authors


More by this author
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0001-9465-8214
More by this author
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0003-4550-0431
More by this author
Division:
MSD
Sub department:
Population Health
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0002-1004-4395
Publisher:
F1000Research Publisher's website
Journal:
Wellcome Open Res Journal website
Volume:
5
Article number:
21
Publication date:
2020-02-07
Acceptance date:
2020-01-30
DOI:
ISSN:
2398-502X
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1124691
Local pid:
pubs:1124691
Deposit date:
2020-08-14

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