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Journal article

Long-term efficacy and safety comparison of liraglutide, glimepiride and placebo, all in combination with metformin in type 2 diabetes: 2-year results from the LEAD-2 study.

Abstract:

AIMS: To investigate efficacy and safety of dual therapy with liraglutide and metformin in comparison to glimepiride and metformin, and metformin monotherapy over 2 years in patients with type 2 diabetes. METHODS: In the 26-week the Liraglutide Effect and Action in Diabetes (LEAD)-2 core trial, patients (n = 1091) were randomized (2 : 2 : 2 : 1: 2) to liraglutide (0.6, 1.2 or 1.8 mg once-daily), placebo or glimepiride; all with metformin. Patients were enrolled if they were 18-80 years old w...

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Publication status:
Published

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Publisher copy:
10.1111/dom.12012

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Journal:
Diabetes, obesity and metabolism
Volume:
15
Issue:
3
Pages:
204-212
Publication date:
2013-03-05
DOI:
EISSN:
1463-1326
ISSN:
1462-8902
URN:
uuid:c756aa0d-f0dd-401b-ba59-ef5a965d1ae9
Source identifiers:
356631
Local pid:
pubs:356631

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