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Amphetamine promotes task-dependent recovery following focal cortical ischaemic lesions in the rat.

Abstract:

This study investigated the effect of amphetamine (AMP) on skilled forelimb use following focal cortical ischaemic lesions in the rat. Unilateral lesions were produced by a novel method of intracortical microinjection of endothelin-1 (ET-1), intended to principally target the forelimb representation zone in primary motor-primary somatosensory cortex. Lesions were placed in the hemisphere contralateral to the preferred limb and produced deficits in skilled forelimb use on two tasks: the paw re...

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Publication status:
Published

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Publisher copy:
10.1016/j.bbr.2005.06.027

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
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Journal:
Behavioural brain research
Volume:
165
Issue:
1
Pages:
98-109
Publication date:
2005-11-05
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
URN:
uuid:c73e07ff-15a7-4c40-95a9-280e7ac31f90
Source identifiers:
30649
Local pid:
pubs:30649

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