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Prior ingestion of exogenous ketone monoester attenuates the glycaemic response to an oral glucose tolerance test in healthy young individuals

Abstract:

The main objectives of the present study were: (i) to determine whether acute ingestion of ketone monoester (Kme); (R)‐3‐hydroxybutyl (R)‐3‐hydroxybutyrate impacts plasma glucose levels during a standardized oral glucose tolerance test (OGTT) and (ii) to compare changes in insulin concentrations and estimates of insulin sensitivity after acute Kme supplementation. Twenty healthy participants (n = 10 males/females) aged between 18 and 35 years took part in a randomized cross‐over study. After ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1113/jp275709

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology Anatomy and Genetics
Role:
Author
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Role:
Author
ORCID:
0000-0002-9796-2008
More from this funder
Funding agency for:
Little, J
Grant:
16890
Publisher:
Wiley Publisher's website
Journal:
Journal of Physiology Journal website
Volume:
596
Issue:
8
Pages:
1385-1395
Publication date:
2018-02-15
Acceptance date:
2018-01-30
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
Pmid:
29446830
Source identifiers:
826843
Language:
English
Pubs id:
pubs:826843
UUID:
uuid:c72208f5-1ab3-4b42-b4dc-35522f307d37
Local pid:
pubs:826843
Deposit date:
2018-03-09

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