Quantitation of bacteria in blood of typhoid fever patients and relationship between counts and clinical features, transmissibility, and antibiotic resistance.

Journal article

Salmonella typhi was isolated from 369 and Salmonella paratyphi A was isolated from 6 of 515 Vietnamese patients with suspected enteric fever. Compared with conventional broth culture of blood, direct plating of the buffy coat had a diagnostic sensitivity of 99.5% (95% confidence interval [CI], 97.1 to 100%). Blood bacterial counts were estimated by the pour plate method. The median S. typhi count in blood was 1 CFU/ml (range, <0.3 to 387 CFU/ml), of which a mean of 63% (95% CI, 58 to 67%)...

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Authors: Wain, J; Diep, T; Ho, V; Walsh, A; Nguyen, T

• Publication status: Published
• Journal: Journal of clinical microbiology
• Volume: 36
• Issue: 6
• Pages: 1683-1687
• Publication date: 1998-06-01
• EISSN: 1098-660X
• ISSN: 0095-1137
• Language: English
• Keywords: Drug Resistance, Multiple; Adolescent; Microbial Sensitivity Tests; Male; Bacteremia; Leukocytes; Humans; Drug Resistance, Microbial; Culture Media; Feces; Prospective Studies; Salmonella typhi; Blood; Female; Adult; Typhoid Fever; Sensitivity and Specificity; Time Factors; Colony Count, Microbial; Child