Journal article icon

Journal article

Functional impairment of cytomegalovirus specific CD8 T cells predicts high-level replication after renal transplantation.

Abstract:

Human cytomegalovirus (HCMV) remains an important cause of morbidity after allotransplantation, causing a range of direct effects including hepatitis, pneumonitis, enteritis and retinitis. A dominant risk factor for HCMV disease is high level viral replication in blood but it remains unexplained why only a subset of patients develop such diseases. In this detailed study of 25 renal transplant recipients, we show that functional impairment of HCMV specific CD8 T cells in the production of inte...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Volume:
8
Issue:
5
Pages:
990-999
Publication date:
2008-05-01
DOI:
EISSN:
1600-6143
ISSN:
1600-6135
Source identifiers:
22313

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP