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Non-B27 MHC associations of ankylosing spondylitis.

Abstract:

Ankylosing spondylitis (AS) has been associated with human leukocyte antigen (HLA)-B27 for over 30 years; however, the mechanism of action has remained elusive. Although many studies have reported associations between AS and other genes in the major histocompatibility complex (MHC) in AS, no conclusive results have emerged. To investigate the contribution of non-B27 MHC genes to AS, a large cohort of AS families and controls were B27 typed and genotyped across the region. Interrogation of the...

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Publication status:
Published

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Publisher copy:
10.1038/sj.gene.6364362

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Journal:
Genes and immunity
Volume:
8
Issue:
2
Pages:
115-123
Publication date:
2007-03-01
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Source identifiers:
108391
Language:
English
Keywords:
Pubs id:
pubs:108391
UUID:
uuid:c706477f-8114-4413-8c53-e17b81972d56
Local pid:
pubs:108391
Deposit date:
2012-12-19

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