- Abstract:
-
Microscopic MRI (microMRI) is an emerging technique for high-throughput phenotyping of transgenic mouse embryos, and is capable of visualising abnormalities in cardiac development. To identify cardiac defects in embryos, we have optimised embryo preparation and MR acquisition parameters to maximise image quality and assess the phenotypic changes in chromodomain helicase DNA-binding protein 7 (Chd7) transgenic mice. microMRI methods rely on tissue penetration with a gadolinium chelate contrast...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/nbm.1400
-
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- Journal:
- NMR in biomedicine
- Volume:
- 22
- Issue:
- 8
- Pages:
- 857-866
- Publication date:
- 2009-10-05
- DOI:
- EISSN:
-
1099-1492
- ISSN:
-
0952-3480
- URN:
-
uuid:c705113c-1a04-4c63-b5a6-47b337f7d755
- Source identifiers:
-
105889
- Local pid:
- pubs:105889
- Copyright date:
- 2009
Journal article
Cardiac phenotyping in ex vivo murine embryos using microMRI.
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