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Characterization of fHbp, nhba (gna2132), nadA, porA, sequence type (ST), and genomic presence of IS1301 in group B meningococcal ST269 clonal complex isolates from England and Wales.

Abstract:

Highly effective glycoconjugate vaccines exist against four of the five major pathogenic groups of meningococci: A, C, W-135, and Y. An equivalent vaccine against group B meningococci (menB) has remained elusive due to the poorly immunogenic capsular polysaccharide. A promising alternative, the investigational recombinant menB (rMenB)- outer membrane vesicle (OMV) vaccine, contains fHBP, NHBA (previously GNA2132), NadA, and outer membrane vesicles (OMVs) from the New Zealand MeNZB vaccine. Me...

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Publisher copy:
10.1128/jcm.00936-09

Authors


Lucidarme, J More by this author
Comanducci, M More by this author
Findlow, J More by this author
Kaczmarski, EB More by this author
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Journal:
Journal of clinical microbiology
Volume:
47
Issue:
11
Pages:
3577-3585
Publication date:
2009-11-05
DOI:
EISSN:
1098-660X
ISSN:
0095-1137
URN:
uuid:c6f60bb4-d6b2-4b31-9a62-19067ba13c1e
Source identifiers:
249477
Local pid:
pubs:249477

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