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System and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue

Subtitle:
US 8,995,740
Abstract:

Improved systems and methods for the analysis of digital images are provided. More particularly, the present disclosure provides for improved systems and methods for the analysis of digital images of biological tissue samples. Exemplary embodiments provide for: i) segmenting, ii) grouping, and iii) quantifying molecular protein profiles of individual cells in terms of Sub cellular compartments (nuclei, membrane, and cytoplasm). The systems and methods of the present disclosure advantageously ...

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Publication status:
Granted

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Authors


Santamaria-Pang, A More by this author
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Subgroup:
Oxford Ludwig Institute
Padfield, D More by this author
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Acceptance date:
2015-03-31
Patent number:
US8995740B2
Pubs id:
pubs:959629
URN:
uri:c6ec4a93-ad53-4aee-b9ed-a45ea00b0e5d
UUID:
uuid:c6ec4a93-ad53-4aee-b9ed-a45ea00b0e5d
Local pid:
pubs:959629
Keywords:

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