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Phylodynamics helps to evaluate the impact of an HIV prevention intervention

Abstract:

Assessment of the long-term population-level effects of HIV interventions is an ongoing public health challenge. Following the implementation of a Transmission Reduction Intervention Project (TRIP) in Odessa, Ukraine, in 2013–2016, we obtained HIV pol gene sequences and used phylogenetics to identify HIV transmission clusters. We further applied the birth-death skyline model to the sequences from Odessa (n = 275) and Kyiv (n = 92) in order to estimate changes in the epidemic’s effective repro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/v12040469

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Division:
MPLS
Department:
Zoology
Sub department:
Zoology
Role:
Author
Publisher:
MDPI Publisher's website
Journal:
Viruses Journal website
Publication date:
2020-04-20
Acceptance date:
2020-04-15
DOI:
EISSN:
1999-4915
ISSN:
1999-4915
Keywords:
Pubs id:
1100432
Local pid:
pubs:1100432
Deposit date:
2020-04-16

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