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Elevated levels of endothelial cell-derived microparticles following short-term withdrawal of continuous positive airway pressure in patients with obstructive sleep apnea: data from a randomized controlled trial.

Abstract:

BACKGROUND: Obstructive sleep apnea has been associated with impaired endothelial function; however, the mechanisms underlying this association are not completely understood. Cell-derived microparticles may provide a link between obstructive sleep apnea and endothelial dysfunction. OBJECTIVES: This randomized controlled trial aimed to examine the effect of a 2-week withdrawal of continuous positive airway pressure (CPAP) therapy on levels of circulating microparticles. METHODS: Forty-one obst...

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Publication status:
Published

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Publisher copy:
10.1159/000342877

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division, Biomedical Research Centre
Role:
Author
Journal:
Respiration; international review of thoracic diseases
Volume:
85
Issue:
6
Pages:
478-485
Publication date:
2013-01-01
DOI:
EISSN:
1423-0356
ISSN:
0025-7931
URN:
uuid:c6b5f64f-0272-4195-b15e-c53958f8c140
Source identifiers:
363804
Local pid:
pubs:363804

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