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Population variation in anti-S. aureus IgG isotypes influences surface protein A mediated immune subversion

Abstract:

Staphylococcus aureus is a pathogen which causes life-threatening infection, the incidence of which rises during adult life. This, together with the emergence of drug-resistant strains and the expansion of more susceptible elderly populations, represents the rationale for the ongoing development of S. aureus vaccines targeting adult populations. Humoral responses to S. aureus naturally develop early in life, influence susceptibility to infection, and potentially influence the effect of vaccin...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.vaccine.2016.02.034

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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
Role:
Author
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National Institute for Health Research More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Vaccine Journal website
Volume:
34
Issue:
15
Pages:
1792-1799
Publication date:
2016-04-04
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
URN:
uuid:c6a5fee6-a294-49c5-bac8-af0d76d3ca0c
Source identifiers:
609044
Local pid:
pubs:609044

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