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Journal article

Automated solid-phase extraction method for the determination of piperaquine in capillary blood applied onto sampling paper by liquid chromatography.

Abstract:

A bioanalytical method for the determination of piperaquine in 100 microL blood applied onto sampling paper, by solid-phase extraction and liquid chromatography, has been developed and validated. Blood spots were cut into small pieces prior to addition of 0.3M perchloric acid, acetonitrile and phosphate buffer containing an internal standard. The liquid phase was loaded onto a mixed phase cation-exchange (MPC) solid-phase extraction column. Piperaquine and the internal standard were analysed ...

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Publication status:
Published

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Journal:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Volume:
809
Issue:
1
Pages:
43-49
Publication date:
2004-09-05
DOI:
EISSN:
1873-376X
ISSN:
1570-0232
URN:
uuid:c691ac74-8d30-4154-a0f5-688f06dd550c
Source identifiers:
10919
Local pid:
pubs:10919

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