Back to Search

Journal article

CD8+ T cell responses to human immunodeficiency viruses type 2 (HIV-2) and type 1 (HIV-1) gag proteins are distinguishable by magnitude and breadth but not cellular phenotype

Abstract:: The mechanisms underlying the relatively slow progression of human immunodeficiency virus type 2 (HIV-2) compared with HIV-1 infection are undefined and could be a result of more effective immune responses. We used HIV-2 and HIV-1 IFN-γ enzyme-linked immunospot assays to evaluate CD8+ T cell responses in antiretroviral-naive HIV-2-('HIV-2+') and HIV-1-infected ('HIV-1+') individuals. Gag-specific responses were detected in the majority of HIV-2+ and HIV-1+ subjects. Overlapping gag peptide an...
Expand abstract
Collapse abstract

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Gillespie, G., Pinheiro, S., Sayeid-Al-Jamee, M., Alabi, A., Kaye, S., Sarge-Njie, R., Njai, H., Joof, K., Jaye, A., Whittle, H., Rowland-Jones, S., & Dorrell, L. (2005). CD8+ T cell responses to human immunodeficiency viruses type 2 (HIV-2) and type 1 (HIV-1) gag proteins are distinguishable by magnitude and breadth but not cellular phenotype. European Journal of Immunology, 35(5), 1445–1453.

MLA Style

Gillespie, G., et al. “CD8+ T Cell Responses to Human Immunodeficiency Viruses Type 2 (HIV-2) and Type 1 (HIV-1) Gag Proteins Are Distinguishable by Magnitude and Breadth but Not Cellular Phenotype.” European Journal of Immunology, vol. 35, no. 5, 2005, pp. 1445–53.

Chicago Style

Gillespie, G, S Pinheiro, M Sayeid-Al-Jamee, A Alabi, S Kaye, R Sarge-Njie, H Njai, et al. 2005. “CD8+ T Cell Responses to Human Immunodeficiency Viruses Type 2 (HIV-2) and Type 1 (HIV-1) Gag Proteins Are Distinguishable by Magnitude and Breadth but Not Cellular Phenotype.” European Journal of Immunology 35 (5): 1445–53.
Tweet
Print

Access Document

Publisher copy:: 10.1002/eji.200526007

Authors

+ Gillespie, G More by this author

Role:

Author

+ Pinheiro, S More by this author

Role:

Author

+ Sayeid-Al-Jamee, M More by this author

Role:

Author

+ Alabi, A More by this author

Role:

Author

+ Kaye, S More by this author

Role:

Author

More authors...

Bibliographic Details

Journal:: European Journal of Immunology
Volume:: 35
Issue:: 5
Pages:: 1445-1453
Publication date:: 2005-05-01
DOI:: 10.1002/eji.200526007
ISSN:: 0014-2980

Item Description

Language:: English
Keywords:: HIV-1

HIV-2

Perforin

CD8+ T cell

IFN-γ
Pubs id:: pubs:176676
UUID:: uuid:c68c617f-9e89-4f22-8491-8ec2357068f6
Local pid:: pubs:176676
Source identifiers:: 176676
Deposit date:: 2013-02-20

Terms of use

Copyright date:: 2005

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Metrics

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP