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Multiscale modelling of tumour growth and therapy: The influence of vessel normalisation on chemotherapy

Abstract:

Following the poor clinical results of antiangiogenic drugs, particularly when applied in isolation, tumour biologists and clinicians are now turning to combinations of therapies in order to obtain better results. One of these involves vessel normalisation strategies. In this paper, we investigate the effects on tumour growth of combinations of antiangiogenic and standard cytotoxic drugs, taking into account vessel normalisation. An existing multiscale framework is extended to include new ele...

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Publisher copy:
10.1080/10273660600968994

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
Journal:
Computational and Mathematical Methods in Medicine
Volume:
7
Issue:
2-3
Pages:
85-119
Publication date:
2006-06-01
DOI:
EISSN:
1748-6718
ISSN:
1748-670X
Source identifiers:
148238
Language:
English
Keywords:
Pubs id:
pubs:148238
UUID:
uuid:c681bc96-794d-46db-ad94-26fabb8fb9c7
Local pid:
pubs:148238
Deposit date:
2012-12-19

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