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Journal article

Requirement of fission yeast Cid14 in polyadenylation of rRNAs.

Abstract:

Polyadenylation in eukaryotes is conventionally associated with increased nuclear export, translation, and stability of mRNAs. In contrast, recent studies suggest that the Trf4 and Trf5 proteins, members of a widespread family of noncanonical poly(A) polymerases, share an essential function in Saccharomyces cerevisiae that involves polyadenylation of nuclear RNAs as part of a pathway of exosome-mediated RNA turnover. Substrates for this pathway include aberrantly modified tRNAs and precursors...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Journal:
Molecular and cellular biology
Volume:
26
Issue:
5
Pages:
1710-1721
Publication date:
2006-03-05
DOI:
EISSN:
1098-5549
ISSN:
0270-7306
URN:
uuid:c67dea6b-a85f-40a1-98b2-2000ca6749af
Source identifiers:
28378
Local pid:
pubs:28378

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