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Circulating levels of insulin-like growth factor-II/mannose-6-phosphate receptor in obesity and type 2 diabetes.

Abstract:

OBJECTIVE: The extracellular domain of the insulin-like growth factor II/mannose-6-phosphate receptor (IGF-II/M6P-R) is present in the circulation, but its relationship with plasma IGF-II is largely unknown. As IGF-II appears to be nutritionally regulated, we studied the impact of obesity, type 2 diabetes (T2D) and weight loss on circulating levels of IGF-II and its soluble receptor. METHODS: Twenty-three morbidly obese non-diabetic subjects were studied before and after gastric banding (GB),...

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Publication status:
Published

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Publisher copy:
10.1016/j.ghir.2009.12.005

Authors


Jeyaratnaganthan, N More by this author
Højlund, K More by this author
Kroustrup, JP More by this author
Larsen, JF More by this author
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Journal:
Growth hormone and IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Volume:
20
Issue:
3
Pages:
185-191
Publication date:
2010-06-05
DOI:
EISSN:
1532-2238
ISSN:
1096-6374
URN:
uuid:c66da271-0b60-40eb-becc-f4e37ee67257
Source identifiers:
55395
Local pid:
pubs:55395

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