Journal article
Coma in fatal adult human malaria is not caused by cerebral oedema.
- Abstract:
-
BACKGROUND: The role of brain oedema in the pathophysiology of cerebral malaria is controversial. Coma associated with severe Plasmodium falciparum malaria is multifactorial, but associated with histological evidence of parasitized erythrocyte sequestration and resultant microvascular congestion in cerebral vessels. To determine whether these changes cause breakdown of the blood-brain barrier and resultant perivascular or parenchymal cerebral oedema, histology, immunohistochemistry and image ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Thrasher Research Fund
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Department of Health NIHR Biomedical Research Centres
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Wellcome Trust
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John Fell Fund
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Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Malaria journal Journal website
- Volume:
- 10
- Issue:
- 1
- Pages:
- 267
- Publication date:
- 2011-01-01
- DOI:
- EISSN:
-
1475-2875
- ISSN:
-
1475-2875
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:c66b1691-8323-408c-9eec-5600e5cb9edc
- Local pid:
- pubs:186560
- Source identifiers:
-
186560
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Medana et al
- Copyright date:
- 2011
- Notes:
- © 2011 Medana et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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