Journal article : Review
The role of epigenetics and immunological imbalance in the etiopathogenesis of psoriasis and psoriatic arthritis
- Abstract:
-
Psoriasis (Ps) and psoriatic arthritis (PsA) represent a clinical and immunopathogenic continuum, called psoriatic disease, cumulatively affecting approximately 3% of the general population. Psoriatic disease is a chronic inflammatory disorder affecting the skin and musculoskeletal system. The immuno-pathogenesis is characterized by an activation of the TNF/IL-23/IL-17 cytokine axis, leading to an immunologic imbalance of T-cells resident in all affected tissues, mainly entheses. In the major...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, 692.0KB, Terms of use)
-
- Publisher copy:
- 10.1177/1759720x19886505
Authors
Funding
Bibliographic Details
- Publisher:
- SAGE Publications
- Journal:
- Therapeutic Advances in Musculoskeletal Disease More from this journal
- Volume:
- 11
- Publication date:
- 2019-11-06
- Acceptance date:
- 2019-10-10
- DOI:
- EISSN:
-
1759-7218
- ISSN:
-
1759-720X
- Pmid:
-
31723358
Item Description
- Language:
-
English
- Keywords:
- Subtype:
-
Review
- Pubs id:
-
1073131
- Local pid:
-
pubs:1073131
- Deposit date:
-
2020-06-11
Terms of use
- Copyright holder:
- Frischknecht et al.
- Copyright date:
- 2019
- Rights statement:
- © The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
- Licence:
- CC Attribution-NonCommercial (CC BY-NC)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record