Journal article
Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing
- Abstract:
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Gene expression can be regulated by transcriptional or post-transcriptional gene silencing. Recently, we described nuclear nascent RNA silencing that is mediated by Dicer-dependent tRNA-derived small RNA molecules. In addition to tRNA, RNA polymerase III also transcribes vault RNA, a component of the ribonucleoprotein complex vault. Here, we show that Dicer-dependent small vault RNA1-2 (svtRNA1-2) associates with Argonaute 2 (Ago2). Although endogenous vtRNA1-2 is present mostly in the cyt...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 3.8MB, Terms of use)
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- Publisher copy:
- 10.26508/lsa.202302054
Authors
Bibliographic Details
- Publisher:
- Rockefeller University Press
- Journal:
- Life Science Alliance More from this journal
- Volume:
- 6
- Issue:
- 6
- Article number:
- e202302054
- Publication date:
- 2023-04-10
- Acceptance date:
- 2023-03-28
- DOI:
- ISSN:
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2575-1077
- Pmid:
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37037596
Item Description
- Language:
-
English
- Keywords:
- Pubs id:
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1337395
- Local pid:
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pubs:1337395
- Deposit date:
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2023-04-18
Terms of use
- Copyright holder:
- Alagia et al.
- Copyright date:
- 2023
- Rights statement:
- © 2023 Alagia et al. This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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