Journal article
Genetic variants of MICB and PLCE1 and associations with the laboratory features of dengue
- Abstract:
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Background
Expand abstract
A previous genome-wide association study identified 2 susceptibility loci for severe dengue at MICB rs3132468 and PLCE1 rs3740360 and further work showed these mutations to be also associated with less severe clinical presentations. The aim of this study was to determine if these specific loci were associated with laboratory features of dengue that correlate with clinical severity with the aim of elucidating the functional basis of these genetic variants.
Methods
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 353.4KB, Terms of use)
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- Publisher copy:
- 10.1186/s12879-017-2514-6
Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central
- Journal:
- BMC Infectious Diseases More from this journal
- Volume:
- 17
- Pages:
- 412
- Publication date:
- 2017-06-09
- Acceptance date:
- 2017-06-01
- DOI:
- EISSN:
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1471-2334
Item Description
- Language:
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English
- Keywords:
- Pubs id:
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pubs:700547
- UUID:
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uuid:c64bffcf-8107-4d4e-9269-945de4fb2f98
- Local pid:
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pubs:700547
- Source identifiers:
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700547
- Deposit date:
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2017-06-24
Terms of use
- Copyright holder:
- Whitehorn et al
- Copyright date:
- 2017
- Notes:
- © The Author(s) 2017. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
- Licence:
- CC Attribution (CC BY)
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