Journal article
Emergence of young human genes after a burst of retroposition in primates
- Abstract:
-
The origin of new genes through gene duplication is fundamental to the evolution of lineage- or species-specific phenotypic traits. In this report, we estimate the number of functional retrogenes on the lineage leading to humans generated by the high rate of retroposition (retroduplication) in primates. Extensive comparative sequencing and expression studies coupled with evolutionary analyses and simulations suggest that a significant proportion of recent retrocopies represent bona fide human...
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Bibliographic Details
- Journal:
- PLoS Biology
- Volume:
- 3
- Issue:
- 11
- Pages:
- 1970-1979
- Publication date:
- 2005-11-01
- DOI:
- EISSN:
-
1545-7885
- ISSN:
-
1544-9173
Item Description
- Language:
- English
- Pubs id:
-
pubs:345444
- UUID:
-
uuid:c63d014e-081b-430b-b50a-e2b7c4664d79
- Local pid:
- pubs:345444
- Source identifiers:
-
345444
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2005
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