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Lack of association of angiotensin II type 1 receptor gene polymorphism with diabetic nephropathy in insulin-dependent diabetes mellitus.

Abstract:

Several observations suggest that inherited factors are influential in the development of nephropathy in patients with insulin-dependent diabetes mellitus (IDDM). Genetic components of the renin angiotensin system are possible candidate genes. The aim of this study was to determine the role of the hypertension associated angiotensin II type 1 receptor (AT1R) gene A1166C polymorphism in susceptibility to nephropathy in IDDM. We examined 264 Caucasoid patients with IDDM and overt nephropathy (a...

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Authors


Chowdhury, TA More by this author
Gibson, SP More by this author
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Journal:
Diabetic medicine : a journal of the British Diabetic Association
Volume:
14
Issue:
10
Pages:
837-840
Publication date:
1997-10-05
DOI:
EISSN:
1464-5491
ISSN:
0742-3071
URN:
uuid:c6360cb4-c63a-4d0c-8590-f8dc80c4519f
Source identifiers:
176448
Local pid:
pubs:176448

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