- Abstract:
-
[1-(13)C] pyruvate pre-polarized via DNP has been used in animal models to probe changes in metabolic enzyme activities in vivo. To more accurately assess the metabolic state and its change from disease progression or therapy in a specific region or tissue in vivo, it may be desirable to separate the downstream (13)C metabolite signals resulting from the metabolic activity within the tissue of interest and those brought into the tissue by perfusion. In this study, a spectral-spatial saturatio...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.jmr.2009.06.021
-
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- Journal:
- Journal of magnetic resonance (San Diego, Calif. : 1997)
- Volume:
- 200
- Issue:
- 2
- Pages:
- 344-348
- Publication date:
- 2009-10-05
- DOI:
- EISSN:
-
1096-0856
- ISSN:
-
1090-7807
- URN:
-
uuid:c6316111-c459-4b38-affd-2de9f5e554d7
- Source identifiers:
-
441913
- Local pid:
- pubs:441913
- Copyright date:
- 2009
Journal article
Design of spectral-spatial outer volume suppression RF pulses for tissue specific metabolic characterization with hyperpolarized 13C pyruvate.
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