Journal article icon

Journal article

Mechanical stimulation of the pro-angiogenic capacity of human fracture haematoma: involvement of VEGF mechano-regulation.

Abstract:

Compromised angiogenesis appears to be a major limitation in various suboptimal bone healing situations. Appropriate mechanical stimuli support blood vessel formation in vivo and improve healing outcomes. However, the mechanisms responsible for this association are unclear. To address this question, the paracrine angiogenic potential of early human fracture haematoma and its responsiveness to mechanical loading, as well as angiogenic growth factors involved, were investigated in vitro. Human ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.bone.2010.05.026

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Expand authors...
Journal:
Bone
Volume:
47
Issue:
2
Pages:
438-444
Publication date:
2010-08-01
DOI:
EISSN:
1873-2763
ISSN:
8756-3282
Source identifiers:
66216
Language:
English
Keywords:
Pubs id:
pubs:66216
UUID:
uuid:c60a02e9-d617-4497-a84e-37e09eda53aa
Local pid:
pubs:66216
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP