Journal article icon

Journal article

GOST: A generic ordinal sequential trial design for a treatment trial in an emerging pandemic.

Abstract:

BACKGROUND: Conducting clinical trials to assess experimental treatments for potentially pandemic infectious diseases is challenging. Since many outbreaks of infectious diseases last only six to eight weeks, there is a need for trial designs that can be implemented rapidly in the face of uncertainty. Outbreaks are sudden and unpredictable and so it is essential that as much planning as possible takes place in advance. Statistical aspects of such trial designs should be evaluated and discus...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pntd.0005439

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More from this funder
Grant:
PREPARE (602525
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
11
Issue:
3
Pages:
e0005439
Publication date:
2017-03-09
Acceptance date:
2017-02-27
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Source identifiers:
685314
Language:
English
Keywords:
Pubs id:
pubs:685314
UUID:
uuid:c5fa1393-f7ae-4d78-b7e4-43b9b726cbef
Local pid:
pubs:685314
Deposit date:
2017-03-21

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP