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GOST: A generic ordinal sequential trial design for a treatment trial in an emerging pandemic.

Abstract:

BACKGROUND: Conducting clinical trials to assess experimental treatments for potentially pandemic infectious diseases is challenging. Since many outbreaks of infectious diseases last only six to eight weeks, there is a need for trial designs that can be implemented rapidly in the face of uncertainty. Outbre...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pntd.0005439

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Department:
Oxford, MSD, NDM, Tropical Medicine
Role:
Author
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Grant:
PREPARE (602525)
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
11
Issue:
3
Pages:
e0005439
Publication date:
2017-03-09
Acceptance date:
2017-02-27
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Pubs id:
pubs:685314
URN:
uri:c5fa1393-f7ae-4d78-b7e4-43b9b726cbef
UUID:
uuid:c5fa1393-f7ae-4d78-b7e4-43b9b726cbef
Local pid:
pubs:685314
Language:
English
Keywords:

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