Journal article
Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning
- Abstract:
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Background: A major challenge in the application of marrow transplantation as a route to immunological tolerance of a transplanted organ is to achieve hematopoietic stem cell (HSC) engraftment with minimal myelosuppressive treatments.
Expand abstract
Results: We here describe a combined antibody protocol which can achieve long-term engraftment with clinically relevant doses of MHC-mismatched bone marrow, without the need for myelosuppressive drugs. Alt...
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 288.8KB)
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- Publisher copy:
- 10.1186/1471-2172-7-9
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Authors
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Immunology Journal website
- Volume:
- 7
- Article number:
- 9
- Publication date:
- 2006-04-25
- Acceptance date:
- 2006-04-25
- DOI:
- EISSN:
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1471-2172
- Source identifiers:
-
11576
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:11576
- UUID:
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uuid:c5f2c719-03ff-40b8-8aa0-e74dc0c3c4f2
- Local pid:
- pubs:11576
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Graca et al
- Copyright date:
- 2006
- Notes:
- © 2006 Graca et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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