- Abstract:
-
The Zika virus (ZIKV) epidemic in the Americas established ZIKV as a major public health threat and uncovered its association with severe diseases, including microcephaly. However, genetic epidemiology in some at-risk regions, particularly Central America and Mexico, remains limited. We report 61 ZIKV genomes from this region, generated using metagenomic sequencing with ZIKV-specific enrichment, and combine phylogenetic, epidemiological, and environmental data to reconstruct ZIKV transmission...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 3.9mb)
-
- Publisher copy:
- 10.1016/j.chom.2018.04.017
-
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- Grant:
- T32HD040128
- R01LM010812
- R01LM011965
- R01AI099631
- P01AI106695
- U19 AI118610
- R21AI129455
- R01 HL105704
- Publisher:
- Cell Press Publisher's website
- Journal:
- Cell Host and Microbe Journal website
- Volume:
- 23
- Issue:
- 6
- Pages:
- 855-864.e7
- Publication date:
- 2018-05-24
- Acceptance date:
- 2018-04-26
- DOI:
- EISSN:
-
1934-6069
- ISSN:
-
1931-3128
- Pubs id:
-
pubs:844882
- URN:
-
uri:c5ee16d3-9842-4bdc-ae75-994edebe52cb
- UUID:
-
uuid:c5ee16d3-9842-4bdc-ae75-994edebe52cb
- Local pid:
- pubs:844882
- Copyright holder:
- Thézé, J et al.
- Copyright date:
- 2018
- Notes:
- © 2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license.
Journal article
Genomic epidemiology reconstructs the introduction and spread of Zika virus in Central America and Mexico
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Oxford Martin School
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ETH Zurich
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+ National Institutes of Health
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