Journal article
Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism
- Abstract:
-
BACKGROUND. Adrenal aldosterone excess is the most common cause of secondary hypertension and is associated with increased cardiovascular morbidity. However, adverse metabolic risk in primary aldosteronism extends beyond hypertension, with increased rates of insulin resistance, type 2 diabetes, and osteoporosis, which cannot be easily explained by aldosterone excess.
METHODS. We performed mass spectrometry–based analysis of a 24-hour urine steroid ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- American Society for Clinical Investigation Publisher's website
- Journal:
- JCI insight Journal website
- Volume:
- 2
- Issue:
- 8
- Pages:
- e93136
- Publication date:
- 2017-04-20
- Acceptance date:
- 2017-03-14
- DOI:
- EISSN:
-
2379-3708
- Pmid:
-
28422753
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:963084
- UUID:
-
uuid:c5e245b5-e297-4126-ad3e-6003c482df2a
- Local pid:
- pubs:963084
- Source identifiers:
-
963084
- Deposit date:
- 2019-01-22
Terms of use
- Copyright holder:
- Arlt et al
- Copyright date:
- 2017
- Notes:
- © 2017 Arlt et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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