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Reducing passive drug diffusion from electrophoretic drug delivery devices through co-ion engineering

Abstract:

Implantable electrophoretic drug delivery devices have shown promise for applications ranging from treating pathologies such as epilepsy and cancer to regulating plant physiology. Upon applying a voltage, the devices electrophoretically transport charged drug molecules across an ion-conducting membrane out to the local implanted area. This solvent-flow-free “dry” delivery enables controlled drug release with minimal pressure increase at the outlet. However, a major challenge these devices fac...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1002/advs.202003995

Authors


Publisher:
Wiley
Journal:
Advanced Science More from this journal
Volume:
8
Issue:
12
Article number:
2003995
Publication date:
2021-04-10
DOI:
EISSN:
2198-3844
Language:
English
Keywords:
Pubs id:
1280270
Local pid:
pubs:1280270
Deposit date:
2023-05-22

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