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The TD50: a proposed general convention for the numerical description of the carcinogenic potency of chemicals in chronic-exposure animal experiments.

Abstract:

A generally accepted format for the numerical description of the carcinogenic potency of a particular chemical in a particular strain of animals is desirable so that statements from different sources about potency and attempts by different authors to correlate potency with particular laboratory measurements will be comparable. The choice of an appropriate standard format is to a certain extent arbitrary. In this paper we recommend that the TD50 (tumorigenic dose rate 50) be used. TD50 can be ...

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Publication status:
Published

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Publisher copy:
10.2307/3429856

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Bernstein, L More by this author
Journal:
Environmental health perspectives
Volume:
58
Issue:
DEC
Pages:
1-8
Publication date:
1984-12-05
DOI:
EISSN:
1552-9924
ISSN:
0091-6765
URN:
uuid:c5be57e5-7010-4f85-9fc8-5515881ccfd1
Source identifiers:
42191
Local pid:
pubs:42191

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