- Abstract:
-
Chemokines are a family of low molecular weight proteins with an essential role in leukocyte trafficking during both homeostasis and inflammation. The CC class of chemokines consists of at least 28 members (CCL1-28) that signal through 10 known chemokine receptors (CCR1-10). CC chemokine receptors are expressed predominantly by T cells and monocyte-macrophages, cell types associated predominantly with chronic inflammation occurring over weeks or years. Chronic inflammatory diseases including ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1124/pr.111.005074
-
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- Publisher:
- American Society for Pharmacology and Experimental Therapy
- Journal:
- Pharmacological reviews
- Volume:
- 65
- Issue:
- 1
- Pages:
- 47-89
- Publication date:
- 2013-01-05
- DOI:
- EISSN:
-
1521-0081
- ISSN:
-
0031-6997
- URN:
-
uuid:c5b88418-ad14-4e1e-8e5d-5eb2f451b4eb
- Source identifiers:
-
374210
- Local pid:
- pubs:374210
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
CC chemokine receptors and chronic inflammation--therapeutic opportunities and pharmacological challenges.
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