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Imaging of haemodialysis-associated amyloidosis with 123I-serum amyloid P component.

Abstract:

Long-term haemodialysis is frequently complicated by amyloid deposition in which the fibrils consist of beta 2-microglobulin. Dialysis-related amyloid disease causes extensive morbidity and has been associated with deaths in some cases. All amyloid deposits contain amyloid P component that is derived from the normal circulating protein, serum amyloid P component (SAP). We have used scintigraphic imaging after injection of 123I-labelled SAP to assess the distribution of amyloidosis in 38 patie...

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Publication status:
Published

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Authors


Nelson, SR More by this author
Hawkins, PN More by this author
Richardson, S More by this author
Lavender, JP More by this author
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Journal:
Lancet
Volume:
338
Issue:
8763
Pages:
335-339
Publication date:
1991-08-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:c5abf4c9-baff-41dc-90db-5ea03fc89dcc
Source identifiers:
43691
Local pid:
pubs:43691

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