Imaging of haemodialysis-associated amyloidosis with 123I-serum amyloid P component.

Journal article

Long-term haemodialysis is frequently complicated by amyloid deposition in which the fibrils consist of beta 2-microglobulin. Dialysis-related amyloid disease causes extensive morbidity and has been associated with deaths in some cases. All amyloid deposits contain amyloid P component that is derived from the normal circulating protein, serum amyloid P component (SAP). We have used scintigraphic imaging after injection of 123I-labelled SAP to assess the distribution of amyloidosis in 38 patie...

Expand abstract

Authors: Nelson, SR; Hawkins, P; Richardson, S; Lavender, J; Sethi, D

• Publication status: Published
• Journal: Lancet
• Volume: 338
• Issue: 8763
• Pages: 335-339
• Publication date: 1991-08-01
• DOI: 10.1016/0140-6736(91)90478-8
• EISSN: 1474-547X
• ISSN: 0140-6736
• Language: English
• Keywords: Kidney Failure, Chronic; Joint Diseases; Prospective Studies; Renal Dialysis; Amyloidosis; Time Factors; Iodine Radioisotopes; Injections, Intravenous; Serum Amyloid P-Component; Humans