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Journal article

Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.

Abstract:

Obesity is a major health problem, and many family-based studies have suggested that it has a strong genetic basis. We performed a genome-wide quantitative trait linkage scan for loci influencing BMI in 573 pedigrees from the U.K. We identified genome-wide significant linkage (logarithm of odds = 3.74, between D10S208 and D10S196, genome-wide P=0.0186) on chromosome 10p. The size of our study population and the statistical significance of our findings provide substantial contributions to the ...

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Publication status:
Published

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Publisher copy:
10.2337/db05-1674

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
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Journal:
Diabetes
Volume:
55
Issue:
6
Pages:
1884-1889
Publication date:
2006-06-01
DOI:
EISSN:
1939-327X
ISSN:
0012-1797
Source identifiers:
9440

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