- Abstract:
- A 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria.
- Publication status:
- Published
- Publisher copy:
- 10.1093/infdis/161.3.577
-
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- Journal:
- The Journal of infectious diseases
- Volume:
- 161
- Issue:
- 3
- Pages:
- 577-580
- Publication date:
- 1990-03-05
- DOI:
- EISSN:
-
1537-6613
- ISSN:
-
0022-1899
- URN:
-
uuid:c527f250-92e1-4cb2-97ba-de4c342f215c
- Source identifiers:
-
43292
- Local pid:
- pubs:43292
- Copyright date:
- 1990
Journal article
Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment.
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