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Backing into the future: pharmacological approaches to the management of resistant depression

Abstract:

Pragmatic studies indicate that a substantial number of depressed patients do not remit with current first line antidepressant treatments and after two failed treatment steps the chance of remission with subsequent therapies is around 15%. This article focuses on current evidence for pharmacological treatments in resistant depression as well as possible future developments. For patients who have failed to respond to two antidepressant trials, augmentation with atypical antipsychotic drugs, sp...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1017/S003329171700068X

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Publisher:
Cambridge University Press Publisher's website
Journal:
Psychological Medicine Journal website
Volume:
47
Issue:
15
Pages:
2569-2577
Publication date:
2017-08-25
Acceptance date:
2017-02-28
DOI:
EISSN:
1469-8978
ISSN:
0033-2917
Pubs id:
pubs:685612
URN:
uri:c5214492-27f2-43e0-b57b-35e9e4438644
UUID:
uuid:c5214492-27f2-43e0-b57b-35e9e4438644
Local pid:
pubs:685612

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