Phosphodiester content measured in human liver by in vivo (31) P MR spectroscopy at 7 tesla.
Phosphorus (31P) metabolites are emerging liver disease biomarkers. Of particular interest are phosphomonoester and phosphodiester (PDE) “peaks” that comprise multiple overlapping resonances in 31P spectra. This study investigates the effect of improved spectral resolution at 7 Tesla (T) on quantifying hepatic metabolites in cirrhosis.
Five volunteers were scanned to determine metabolite T1s. Ten volunteers and 11 patients with liver cirrhosis were...Expand abstract
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- Peer review status:
- Peer reviewed
- Copyright holder:
- Valkovic et al
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- © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- CC Attribution (CC BY)
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