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Journal article

Phosphodiester content measured in human liver by in vivo (31) P MR spectroscopy at 7 tesla.

Abstract:

Purpose

Phosphorus (31P) metabolites are emerging liver disease biomarkers. Of particular interest are phosphomonoester and phosphodiester (PDE) “peaks” that comprise multiple overlapping resonances in 31P spectra. This study investigates the effect of improved spectral resolution at 7 Tesla (T) on quantifying hepatic metabolites in cirrhosis.

Methods

Five volunteers were scanned to determine metabolite T1s. Ten volunteers and 11 patients with liver cirrhosis were...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1002/mrm.26635

Authors


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Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
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Department:
Oxford, MSD, Clinical Neurosciences
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Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
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Department:
Oxford, MSD, NDM, NDM Experimental Medicine
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Department:
Oxford, MSD, RDM, RDM Cardiovascular Medicine
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Publisher:
Wiley Publisher's website
Journal:
Magnetic Resonance in Medicine Journal website
Volume:
78
Issue:
6
Pages:
2095–2105
Publication date:
2017-02-15
Acceptance date:
2017-01-17
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
Pubs id:
pubs:683696
URN:
uri:c51d3b2a-c4b4-4750-9aff-492f026a347a
UUID:
uuid:c51d3b2a-c4b4-4750-9aff-492f026a347a
Local pid:
pubs:683696

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