Journal article icon

Journal article

Outcome measures used in ocular gene therapy trials: A scoping review of current practice

Abstract:

Multiple gene therapy trials are occurring for a variety of ophthalmic diseases around the world. The safety of gene therapy in the eye has been established, and the next step is to reliably assess efficacy. This is primarily done through the use of imaging techniques and visual function measures. Standardized visual function assessments, however, were originally developed for a clinical setting and may not be suitable for detecting and quantifying therapeutic changes. This scoping review tak...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.3389/fphar.2019.01076

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-9878-4621
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Pharmacology Journal website
Volume:
10
Article number:
1076
Publication date:
2019-09-18
Acceptance date:
2019-08-23
DOI:
ISSN:
1663-9812
Keywords:
Pubs id:
pubs:1053976
UUID:
uuid:c5199a7d-1346-42dd-b182-60fec9f8c5be
Local pid:
pubs:1053976
Source identifiers:
1053976
Deposit date:
2019-09-18

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP