Immunological defence mechanisms of the gastrointestinal tract.

Journal article

The local immune system is highly complex. The distribution of T-cell subsets between epithelium and lamina propria is not random and may be determined by the micro-environment provided by the expression of the class I and II HLA antigens. Macrophages in the small intestine appear to have the characteristics of antigen-processing cells, whereas colonic macrophages may predominantly be phagocytic cells. Suppression of a systemic immune response by prior oral ingestion of antigen may be mediate...

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Authors: Jewell, D

• Publication status: Published
• Journal: Netherlands journal of medicine
• Volume: 27
• Issue: 7
• Pages: 242-248
• Publication date: 1984-01-01
• EISSN: 1872-9061
• ISSN: 0300-2977
• Language: English
• Keywords: B-Lymphocytes; Epithelial Cells; Epithelium; Immunity, Cellular; Animals; Immunoglobulins; Killer Cells, Natural; Digestive System; Mice; Intestinal Mucosa; Macrophages; T-Lymphocytes; Humans