Axonal damage: a key predictor of outcome in human CNS diseases.

Journal article

Axonal damage has recently been recognized to be a key predictor of outcome in a number of diverse human CNS diseases, including head and spinal cord trauma, metabolic encephalopathies, multiple sclerosis and other white-matter diseases (acute haemorrhagic leucoencephalitis, leucodystrophies and central pontine myelinolysis), infections [malaria, acquired immunodeficiency syndrome (AIDS) and infection with human lymphotropic virus type 1 (HTLV-I) causing HTLV-I-associated myelopathy (HAM)/tro...

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Authors: Medana, I; Esiri, M

• Publication status: Published
• Journal: Brain : a journal of neurology
• Volume: 126
• Issue: Pt 3
• Pages: 515-530
• Publication date: 2003-03-01
• DOI: 10.1093/brain/awg061
• EISSN: 1460-2156
• ISSN: 0006-8950
• Language: English
• Keywords: Adolescent; Humans; Brain Ischemia; Adult; Middle Aged; Aged; Spinal Cord Injuries; Malaria, Cerebral; Demyelinating Diseases; AIDS Dementia Complex; Multiple Sclerosis; Craniocerebral Trauma; Child; Infant; Child, Preschool; Diffuse Axonal Injury; Brain Diseases, Metabolic; Central Nervous System Diseases; Deltaretrovirus Infections; Axons; HIV-1