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Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 59 months in Nimba County, Liberia: an open-label randomized non-inferiority trial.

Abstract:

BACKGROUND: Prospective efficacy monitoring of anti-malarial treatments is imperative for timely detection of resistance development. The in vivo efficacy of artesunate-amodiaquine (ASAQ) fixed-dose combination (FDC) was compared to that of artemether-lumefantrine (AL) among children aged six to 59 months in Nimba County, Liberia, where Plasmodium falciparum malaria is endemic and efficacy data are scarce. METHODS: An open-label, randomized controlled non-inferiority trial compared the genot...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1475-2875-12-251

Authors


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Drugs for Neglected Diseases initiative More from this funder
Doctors Without Borders More from this funder
Publisher:
BioMed Central Ltd. Publisher's website
Journal:
Malar J Journal website
Volume:
12
Issue:
1
Pages:
Article: 251
Publication date:
2013-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:c4fe560c-3e77-43a5-a6f2-d5b97e73dc55
Source identifiers:
414688
Local pid:
pubs:414688

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