Journal article icon

Journal article

A potential biomarker of kidney damage identified by proteomics: preliminary findings.

Abstract:

4-Aminophenol (4-AP) and D-serine are established rodent nephrotoxins that selectively damage renal proximal tubules. In an attempt to understand the mechanism of action of these toxicants in greater detail, a high throughput proteomics approach was used to profile protein changes in the plasma of animals treated with these compounds. Male Fischer 344 and Alderley Park rats were treated with increasing doses of 4-AP or D-serine and plasma samples were collected over time. Control groups recei...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Journal:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Volume:
8
Issue:
3-4
Pages:
272-286
Publication date:
2003-01-01
DOI:
EISSN:
1366-5804
ISSN:
1354-750X
Source identifiers:
321920
Language:
English
Keywords:
Pubs id:
pubs:321920
UUID:
uuid:c4e66ca0-e7f2-42cb-a5b3-1e422dbf4458
Local pid:
pubs:321920
Deposit date:
2014-12-26

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP