Journal article
A potential biomarker of kidney damage identified by proteomics: preliminary findings.
- Abstract:
-
4-Aminophenol (4-AP) and D-serine are established rodent nephrotoxins that selectively damage renal proximal tubules. In an attempt to understand the mechanism of action of these toxicants in greater detail, a high throughput proteomics approach was used to profile protein changes in the plasma of animals treated with these compounds. Male Fischer 344 and Alderley Park rats were treated with increasing doses of 4-AP or D-serine and plasma samples were collected over time. Control groups recei...
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- Publication status:
- Published
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- Publisher copy:
- 10.1080/13547500412331332977
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Bibliographic Details
- Journal:
- Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
- Volume:
- 8
- Issue:
- 3-4
- Pages:
- 272-286
- Publication date:
- 2003-01-01
- DOI:
- EISSN:
-
1366-5804
- ISSN:
-
1354-750X
- Source identifiers:
-
321920
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:321920
- UUID:
-
uuid:c4e66ca0-e7f2-42cb-a5b3-1e422dbf4458
- Local pid:
- pubs:321920
- Deposit date:
- 2014-12-26
Terms of use
- Copyright date:
- 2003
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