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Comparative analysis of the Plasmodium falciparum histidine-rich proteins HRP-I, HRP-II and HRP-III in malaria parasites of diverse origin.

Abstract:

Plasmodium falciparum-infected erythrocytes (IRBC) synthesize 3 histidine-rich proteins: HRP-I or the knob-associated HRP, HRP-II and HRP-III or SHARP. In order to distinguish these proteins immunochemically we prepared monoclonal antibodies which react with HRP-I, HRP-II and HRP-III, and rabbit antisera against synthetic peptides derived from the HRP-II and HRP-III sequences. A comparative analysis of diverse P. falciparum parasites was made using these antibodies and immunoprecipitation or ...

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Publication status:
Published

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Publisher copy:
10.1017/s0031182000057681

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Journal:
Parasitology
Volume:
95 ( Pt 2)
Issue:
02
Pages:
209-227
Publication date:
1987-10-01
DOI:
EISSN:
1469-8161
ISSN:
0031-1820
Language:
English
Keywords:
Pubs id:
pubs:184976
UUID:
uuid:c4cfde4f-fed4-4931-bdd7-ead8f5e3c43e
Local pid:
pubs:184976
Source identifiers:
184976
Deposit date:
2012-12-19

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