- Abstract:
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BACKGROUND: The activation of T lymphocytes by specific antigen is accompanied by the formation of a specialized signaling region termed the immunological synapse, characterized by the clustering and segregation of surface molecules and, in particular, by T cell receptor (TCR) clustering. METHODOLOGY/PRINCIPAL FINDINGS: To better understand TCR motion during cellular activation, we used confocal microscopy and photo-bleaching recovery techniques to investigate the lateral mobility of TCR on ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
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(pdf, 260.2kb)
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- Publisher copy:
- 10.1371/journal.pone.0003913
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 3
- Issue:
- 12
- Pages:
- Article: e3913
- Publication date:
- 2008
- DOI:
- EISSN:
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1932-6203
- URN:
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uuid:c4b1b6ff-b5f6-43fd-94ce-9cf8ea0999d0
- Source identifiers:
-
237231
- Local pid:
- pubs:237231
- Copyright holder:
- Dushek et al.
- Copyright date:
- 2008
- Notes:
- Copyright 2008 Dushek et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery.
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Ligue contre le Cancer
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National Science and Engineering Research Council
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Mathematics in Technology and Complex Systems National Centre of Excellence, Canada
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Fundacao para Ciencia e a Tecnologia, Portugal
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France-Canada Research Fund
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