Journal article
Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery.
- Abstract:
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BACKGROUND: The activation of T lymphocytes by specific antigen is accompanied by the formation of a specialized signaling region termed the immunological synapse, characterized by the clustering and segregation of surface molecules and, in particular, by T cell receptor (TCR) clustering. METHODOLOGY/PRINCIPAL FINDINGS: To better understand TCR motion during cellular activation, we used confocal microscopy and photo-bleaching recovery techniques to investigate the lateral mobility of TCR on ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 260.2KB)
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- Publisher copy:
- 10.1371/journal.pone.0003913
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Authors
Funding
National Science and Engineering Research Council
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Fundacao para Ciencia e a Tecnologia, Portugal
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France-Canada Research Fund
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Mathematics in Technology and Complex Systems National Centre of Excellence, Canada
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Ligue contre le Cancer
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 3
- Issue:
- 12
- Article number:
- e3913
- Publication date:
- 2008-01-01
- DOI:
- EISSN:
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1932-6203
- Source identifiers:
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237231
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:c4b1b6ff-b5f6-43fd-94ce-9cf8ea0999d0
- Local pid:
- pubs:237231
- Deposit date:
- 2012-12-19
Terms of use
- Copyright holder:
- Dushek et al
- Copyright date:
- 2008
- Notes:
- Copyright 2008 Dushek et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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