Journal article icon

Journal article

Isolation and expansion of cardiosphere-derived stem cells

Abstract:

The isolation and in vitro expansion of stem cells from the adult heart may provide a cell therapy for regenerating damaged myocardium. Cardiac stem cells can be isolated via magnetic or fluorescent cell sorting using specific cell-surface markers, including c-kit, Sca-1, and Isl-1. Because these isolation methods yield relatively few cells, substantial in vitro expansion is required to generate sufficient cell numbers for therapy. An alternative method uses cells spontaneously shed from cult...

Expand abstract

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Stuckey, DJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics, BHF Centre of Research Excellence
Ellison, GM More by this author
Expand authors...
Journal:
Current Protocols in Stem Cell Biology
Issue:
SUPPL.16
Publication date:
2011
DOI:
EISSN:
1552-485X
ISSN:
1552-4841
URN:
uuid:c4aef359-d8f4-4a6c-9bee-39b2ea898fd1
Source identifiers:
404090
Local pid:
pubs:404090

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP