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Journal article

Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.

Abstract:
A strategy for the site-specific attachment of 2-deoxy-2-fluorosugars to cysteine and dehydroalanine tagged proteins is reported. When combined with thionation of fluorosugars, such as the widely available (18)F probe 2-deoxy-2-[(18)F]fluoroglucose ([(18)F]FDG), this methodology allows fast and direct access to site-specific [(18)F]FDG-labelled proteins.
Publication status:
Published

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Publisher copy:
10.1039/c1cc13524d

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
Chemical Communications More from this journal
Volume:
47
Issue:
36
Pages:
10010-10012
Publication date:
2011-09-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
Language:
English
Keywords:
Pubs id:
pubs:170099
UUID:
uuid:c4ae5247-b679-4559-bad9-6c98b04bd744
Local pid:
pubs:170099
Source identifiers:
170099
Deposit date:
2012-12-19

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