- Abstract:
-
BACKGROUND: Experimental and epidemiologic evidence have suggested that chronic inflammation may play a critical role in endometrial carcinogenesis. METHODS: To investigate this hypothesis, a two-stage study was carried out to evaluate single-nucleotide polymorphisms (SNP) in inflammatory pathway genes in association with endometrial cancer risk. In stage I, 64 candidate pathway genes were identified and 4,542 directly genotyped or imputed SNPs were analyzed among 832 endometrial cancer cases...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1158/1055-9965.epi-12-0903
-
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- Journal:
- Cancer epidemiology, biomarkers and prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
- Volume:
- 22
- Issue:
- 2
- Pages:
- 216-223
- Publication date:
- 2013-02-05
- DOI:
- EISSN:
-
1538-7755
- ISSN:
-
1055-9965
- URN:
-
uuid:c4995e25-d2c9-4ed2-b29d-b0e520e9bd79
- Source identifiers:
-
384731
- Local pid:
- pubs:384731
- Language:
- English
- Keywords:
- Copyright date:
- 2013
Journal article
Polymorphisms in inflammation pathway genes and endometrial cancer risk.
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